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genotoxic
(redirected from genotoxicity)

    Also found in: Dictionary/thesaurus, Wikipedia 0.02 sec.
genotoxic /ge·no·tox·ic/ (je´no-tok″sik) damaging to DNA: pertaining to agents known to damage DNA, thereby causing mutations, which can result in cancer.
ge·no·tox·ic (jn-tksk)
adj.
Damaging to DNA and thereby capable of causing mutations or cancer.
genotoxic
[jē′nōtok′sik]
capable of altering DNA, thereby causing cancer or mutation.


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? Mentioned in ? References in periodicals archive
 
It is important to investigate the effect of occupational exposure to COEs on genotoxicity in coke oven workers.
Elevated levels of urinary 8-hydroxy-2'-deoxyguanosine, lymphocytic ... by Wu, Tang-Chun / Environmental Health Perspectives
With respect to the timing of these studies, the FDA indicated that the data from the genotoxicity studies and reproductive toxicology studies should be included in the original NDA for SILENOR[TM].
Somaxon Provides Update on SILENOR(TM) Preclinical Program by Business Wire
This timing assumes that the initial NDA submission will include all of the data from the company's completed genotoxicity and ongoing reproductive toxicology studies requested by the FDA, but that the FDA will allow the company to submit the data from the requested carcinogenicity studies at a later date.
Somaxon's SILENOR(TM) Demonstrates Positive Results in Long-Term ... by Business Wire
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