EPA will not conduct in-depth analysis of genotoxicity
or cancer hazards in the risk evaluation of Pigment Violet 29, due to structure-activity evaluation and genotoxicity
studies that do not indicate cancer.
as well as cytotoxicity both collectively account for the assessment of damage in the exposed population either through occupation or by smoking or alcohol intake.
Significantly the extract demonstrated both the protective and the antigenotoxic properties against MMS-induced genotoxicity
Statistical analysis of the micronuclei numbers indicated that the bone substitutes tested in this study presented no genotoxicity
of pesticides on fish at 48 h exposure in the present study is found to be in the order of cypermethrin, chlorpyrifos, malathion, lambda-cyhalothrin and buctril, in peripheral blood erythrocytes.
The cytotoxicity and genotoxicity
evaluations and the human leukocyte degeneration indices were performed after heavy metal concentrations were determined, as the experimental heavy metal concentrations were to be similar to those of the samples.
of heavy metals is mainly related to accumulation of free radicals, clastogenic process or simultaneously to clastogenic and aneugenic action in fish (Nepomuceno et al.
The differential expression of genes associated with genotoxicity
was measured by qRT-PCR.
is defined as the modification of the genetic information in a living cell.
This in vitro test is very useful as a first-tier analysis of cytotoxicity and genotoxicity
, because of the simplicity, low relative cost, versatility and minimum laboratory facilities required for its performance (Khora et al.
The biomonitoring of aquatic genotoxicity
is cardinal for many folds.
associated with oxidative stress is based on the oxidative mechanism of reduction of vanadium(V), generating reactive oxygen species (ROS) such as hydroxyl radicals COH) .