carcinogen

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Related to genotoxic carcinogen: genotoxin

carcinogen

 [kahr-sin´o-jen]
a substance that causes cancer. The Environmental Protection Agency of the U.S. Government has three descriptors for classifying human carcinogenic potential: “known/likely,” “cannot be determined,” and “not likely.”

car·cin·o·gen

(kar-sin'ō-jen, kar'si-nō-jen),
Any cancer-producing substance or organism, such as polycyclic aromatic hydrocarbons, or agents such as in certain types of irradiation.
[carcino- + G, -gen, producing]

carcinogen

/car·cin·o·gen/ (kahr-sin´ah-jen) any substance which causes cancer.carcinogen´ic
epigenetic carcinogen  one that does not itself damage DNA but causes alterations that predispose to cancer.
genotoxic carcinogen  one that reacts directly with DNA or with macromolecules that then react with DNA.

carcinogen

(kär-sĭn′ə-jən, kär′sə-nə-jĕn′)
n.
A cancer-causing substance or agent.

car′ci·no·gen′e·sis (kär′sə-nə-jĕn′ĭ-sĭs) n.
car′cin·o·gen′ic (-jĕn′ĭk) adj.
car′ci·no·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.

carcinogen

[kärsin′əjin]
Etymology: Gk, karkinos + genein, to produce
a substance or agent that causes the development or increases the incidence of cancer. The United States Department of Health and Human Services publishes a biennial report that contains a list of all substances which either are known to be human carcinogens or may reasonably be anticipated to be human carcinogens. carcinogenic, adj.

carcinogen

Oncology Any physical or chemical agent or substance which, when administered by an appropriate route, ↑ incidence of tumors when compared to unexposed control population. See Cocarcinogen, Complete carcinogen, Natural carcinogen, Proximal carcinogen.

car·cin·o·gen

(kahr-sin'ŏ-jen)
Any cancer-producing substance or organism, such as polycyclic aromatic hydrocarbons, or agents such as certain types of irradiation.
[carcino- + G, -gen, producing]

carcinogen

Any CANCER-producing agency.

carcinogen

a substance which is a CANCER-causing agent.

Carcinogen

A substance that is known to cause cancer.
Mentioned in: Eye Cancer

carcinogen

any cancer-inducing substance

carcinogen (kär·sinˑ··jin),

n any agent found to be cancer-causing.

car·cin·o·gen

(kahr-sin'ŏ-jen)
Any cancer-producing substance or organism.
[carcino- + G, -gen, producing]

carcinogen (kärsin´əjen),

n a substance or agent that causes the development or increases the incidence of cancer.

carcinogen

a substance that causes cancer.
References in periodicals archive ?
This analysis confirms that genotoxic carcinogens are generally characterized by an ability to cause tumors in multiple species and at multiple sites (13, 14) whereas nongenotoxic agents tend to exhibit tissue- and species-specific carcinogenicity (Table 11) (4,13,15).
At least," he says, "there is a contrast with tobacco smoke, where genotoxic carcinogens are clearly present and involved along with other types of effects, and carcinogen-DNA adducts have been observed in the breast tissue of exposed women.
The frequency of chromosomal aberrations (CAs) in human peripheral blood lymphocytes (PBLs) measured with the conventional cytogenetic assay in metaphase cells has routinely been used for several decades as a tool to monitor occupational and environmental exposures to genotoxic carcinogens.
These tumors are readily induced by many genotoxic carcinogens, but they may also be induced by virtually any nongenotoxic goitrogen in these rodent species.