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genotoxic

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genotoxic /ge·no·tox·ic/ (je´no-tok″sik) damaging to DNA: pertaining to agents known to damage DNA, thereby causing mutations, which can result in cancer.
ge·no·tox·ic (jn-tksk)
adj.
Damaging to DNA and thereby capable of causing mutations or cancer.

genotoxic
[jē′nōtok′sik]
capable of altering DNA, thereby causing cancer or mutation.

genotoxic [je´no-tok″sik]
damaging to DNA; pertaining to agents (radiation or chemical substances) known to damage DNA, thereby causing mutations or cancer.


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These include leukaemia, brain tumours, genotoxic and neurological effects, neurodegenerative disease, allergic and inflammatory responses, breast cancer, miscarriage and various cardiovascular effects among others.
Metabolic conversion of inorganic As (iAs) to dimethylarsinic acid (DMA) reduces toxicity and facilitates urinary As (uAs) elimination, but the intermediate metabolite monomethylarsonic (MMA) may have increased cytoxic and genotoxic effects.
Ultraviolet radiation is also a genotoxic agent responsible for skin cancer, through the formation of free radicals and DNA damage," said lead researcher Tiago Duarte, formerly of the University of Leicester, and now at the Institute for Molecular and Cellular Biology in Portugal.
 
 
 
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