genotoxic


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Related to genotoxic: genotoxic carcinogen

genotoxic

 [je´no-tok″sik]
damaging to DNA; pertaining to agents (radiation or chemical substances) known to damage DNA, thereby causing mutations or cancer.

ge·no·tox·ic

(jē'nō-toks'ik),
Denoting a substance that by damaging DNA may cause mutation or cancer.
[gene + toxic]

genotoxic

/ge·no·tox·ic/ (je´no-tok″sik) damaging to DNA: pertaining to agents known to damage DNA, thereby causing mutations, which can result in cancer.

genotoxic

[jē′nōtok′sik]
capable of altering DNA, thereby causing cancer or mutation.

genotoxic

adjective Referring to a factor or substance that causes chromosomal or DNA damage.

ge·no·tox·ic

(jē'nō-toks'ik)
Denoting a substance that by damaging DNA may cause mutation or cancer.
References in periodicals archive ?
02-8 mM in human peripheral blood cells in vitro, in order to investigate their genotoxic, cytotoxic and cytostatic potential.
The genotoxic effects of thiocyclam was determined by comparing the number of aberrant cells in division stages for each dose of each pesticide with those of the concurrent negative control are presented in Tables 1, 2, and 3.
Even though the quantitative relationship between cytogenetic damage in reporter cells and cancer risk has not been established, the two-fold increase in chromosomal aberrations in traffic policemen reported by Sree Devi and coworkers (1) indicates a remarkable exposure to genotoxic compounds, which may underpin adverse effects at somatic and germ cell levels.
Wear particles generated by ceramic materials are generally very fine and do not leach out ions that can have cytotoxic or genotoxic effects.
Some organisms such as plants, fish, birds and frogs were also investigated by micronucleus test to detect environmental pollution capable of producing genotoxic damage (Ma et al.
The genotoxic effects of the pesticides as, determined by comparing the number of aberrant cells in division stages for each dose of each pesticide with those of the concurrent negative control in the Mann-Whitney U test are presented in Table 2.
Efficacy of a potentized homeopathic drug (Arsenicum album-30) in reducing genotoxic effects produced by arsenic trioxide in mice: II.
Nuclear abnormalities in erythrocytes, as micronuclei and nuclear buds (BE), are considered potential biomarkers of genotoxic exposure.
Data from 12 children showed significant increases in several genotoxic end points after 3 months of daily treatment with methylphenidate.
According to experts, malachite green is a potential genotoxic carcinogen which, if used in food preparation areas, can indirectly contaminate food.
DNA repair systems play a crucial role in maintaining the genetic integrity against genotoxic attacks and in protecting us from tumoral progress.
No additional purification required - prevents formation of genotoxic by-product impurities associated with sulfuric acids