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genetic screening |
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genetic screening, the process of investigating a specific population of persons for the purpose of detecting the presence of disease, either incipient or overt, such as the generalized screening of all newborns for phenylketonuria. Genetic screening may be used to identify those who possess defective genes, gain information concerning the incidence of a disorder in the population, and provide reproductive information, specifically to those at risk, such as the close relatives of persons affected with inborn errors of metabolism or those in certain ethnic groups who have a high incidence of a particular disease, specifically sickle cell anemia in African-Americans and Tay-Sachs disease in Ashkenazic Jews. When accompanied by education and counseling, mass screening programs can be effective in the management of genetic disorders. See also genetic counseling. genetic screening Molecular diagnostics The screening of a person's serum for molecular markers that indicate an ↑ susceptibility to inherited or acquired diseases with a genetic component GS candidates Cystic fibrosis, PKU, sickle
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President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research predicted that before the end of the century genetic screening and counseling would become major components of both public health and individual medical care. Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australia HIV cohort study. Lea Sevcik, assistant director of the Catholic Organization for Life and Family (COLF), writes that Health Canada has asked for public input on the extent to which genetic screening of embryos should be allowed in Canada. |
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