genetic manipulation


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genetic manipulation

Modification of the genotype or the gene expression of an organism or a cell.
See also: manipulation
References in periodicals archive ?
These results suggest that 708a may be a natural candidate for genetic manipulation experiments that use gentamicin, spectinomycin, streptomycin (8), and nourseothricin (9), and validate the use of laboratory-constructed A(amrABoprA) mutants in such experiments.
Through work on the genetic manipulation of polyketide genes, his laboratory has created novel metabolites, devised methods to purify and study polyketide synthase enzymes, established fermentation routes to pharmaceutically important compounds, and used genetic engineering to develop improved strains of commercially important microorganisms.
is a privately held biotechnology company engaged in the discovery and development of pharmaceuticals by genetic manipulation of biosynthetic pathways of natural products, with an initial focus on polyketides.
Genetic manipulation to selectively enhance the ability of cancer cells to produce these foreign antigens, he says, may stimulate the immune system to eradicate epithelial cancers.
The human neural cells utilized by CytoTherapeutics' researchers are normal, genetically unmodified cells, which do not contain cancer-causing oncogenes or other forms of genetic manipulation.
Through genetic manipulation, the investigators then created a form of tPA that lacked the loop.
Through work on the molecular biology and genetic manipulation of polyketide genes and natural products chemistry, his laboratory has created novel metabolites, devised methods to purify and study polyketide synthase enzymes, and used genetic engineering to develop improved strains of commercially important microorganisms.
But developing a drug-delivery system from endothelial cells may prove difficult even if the basic genetic manipulation is achieved, he adds.
Katz is a noted expert in microbial genetics and anti-infective biology with specific expertise in the molecular biology and genetic manipulation of polyketide biosynthesis.
The genetic manipulation isn't therapeutic, but is designed to help study a promising new cancer treatment.
Baehr, are mice that through a genetic manipulation develop within a three month period a destructive condition of the retina, resembling retinitis pigmentosa.
The Future of Genetic Manipulation is especially bad, even though it has a good four-page glossary.