genetic load


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Related to genetic load: balanced polymorphism

ge·net·ic load

the aggregate of more or less harmful genes that are carried, mostly hidden, in the genome that may be transmitted to descendants and cause morbidity and disease; in classic genetic dynamics, genetic load may be seen as undischarged genetic debts that result from previous mutations, each of which is supposed to exact an average number of lethal equivalents dependent only on the pattern of inheritance, regardless of how mild or severe the phenotype may be.

genetic load

n.
1. The relative difference between the theoretically most fit genotype within a population and the average genotype.
2. The aggregate of deleterious genes that are carried, mostly hidden, in the genomes of a population and may be transmitted to descendants.

genetic load

the average number of accumulated detrimental genes per individual within a population, including those caused by mutation and selection within a recent generation and those inherited from ancestors. Genetic load is expressed in lethal equivalents.

ge·net·ic load

(jĕ-net'ik lōd)
The aggregate of more or less harmful genes that are carried, mostly hidden, in the genome and may be transmitted to descendants and cause disease.

genetic load

The totality of abnormalities caused in each generation by defective genetic material carried in the human gene pool.

genetic load

a measurement of the amount of deleterious genes in a population, calculated as the average number of lethal equivalents per individual.
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References in periodicals archive ?
Most mutations are likely deleterious and recessive and constitute a substantial genetic load on population fitness.
However, once they enter a cell, the acidity in the uptake compartment increases to a pH of 5 to 6 and the vesicles fall apart, releasing their genetic loads into the cell's cytoplasm.