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generalized vaccinia

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generalized vaccinia
n.
A skin eruption following vaccination for smallpox, seen most commonly in people with previously traumatized skin.

vaccinia [vak-sin´e-ah]
the cutaneous and sometimes systemic reactions associated with vaccination with smallpox vaccine. See also cowpox and paravaccinia.
vaccinia gangreno´sa generalized vaccinia with failure to develop antibodies against the virus (due to agammaglobulinemia), with spreading necrosis at the site and metastasis of lesions throughout the body.
generalized vaccinia a condition of widespread vaccinial lesions resulting from sensitivity response to smallpox vaccination and delayed production of neutralizing antibodies.
progressive vaccinia vaccinia gangrenosa.


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21) As compared with persons revaccinated, primary vaccinees had a 10-fold greater risk of eczema vaccinatum (approximately 1 case per 100,000), a 20-fold greater risk of generalized vaccinia (approximately 2 cases per 100,000), and, whereas there were no cases of postvaccinial encephalitis among revaccinees, the risk was approximately 3 cases per million among primary vaccinees.
Compared to vaccination campaigns in England and Wales in 1951 to 1960 (18), the numbers of postvaccinial encephalomyelitis and generalized vaccinia were much higher (Table 1).
Generalized vaccinia (GV) is a typically self-limited adverse event following vaccination (incidence 23.
 
 
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