generalized seizure

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Related to generalized seizure: grand mal seizure, focal seizure, primary generalized epilepsy, complex partial seizure, generalized seizure disorder

generalized seizure

A seizure that originates from multiple brain foci and is characterized by general rather than localized neurologic symptoms, may be tonic-clonic, and may progress from a focal seizure.

generalized seizure

A seizure in which abnormal electrical activity occurs in large areas of the brain. Generalized seizures usually result in loss of consciousness.
See also: seizure


1. the sudden attack or recurrence of a disease.
2. a convulsion or attack of epilepsy.

audiogenic seizure
a seizure brought on by sound.
cerebral seizure
an attack of epilepsy.
epileptiform seizure
focal seizure
see partial seizure (below).
generalized seizure
see grand mal seizure (below).
grand mal seizure
one with no localizing signs. After a brief period of restlessness, there is unconsciousness, generalized muscular activity, excessive salivation, chewing activity, opisthotonos, running movements, and often urination and defecation. The most common type of seizure in dogs and cats.
Jacksonian seizure
partial seizure
one restricted to a focus in the brain; signs correspond to the area affected, e.g. motor activity of an isolated area or limb, hallucinations such as fly catching, apparent blindness, behavioral abnormalities, etc. Called also focal seizures.
petit mal seizure
a mild, very brief generalized seizure. See also petit mal.
photogenic seizure
a seizure brought on by light.
psychomotor seizure
motor seizures accompanied by a psychic stage. There are hallucinations, salivation, pupillary dilatation, mastication, fecal and urinary excretion, and wild running. Seen in dogs with lesions in the pyriform lobe or hippocampus and from poisoning with agenized flour (canine hysteria). Called also running fits.
tetanic seizure
see tetany.
seizure threshold
the level of stimulation at which a seizure is precipitated.
tonic seizure
one in which the muscles are rigid.
tonic-clonic seizure
alternating tonic (rigid muscles) and clonic (jerking of muscles) phases; a grand mal seizure.
References in periodicals archive ?
Intermediate-range efficacy Zonsamide (Zonegran) and levetiracetam Keppra) appear to offer the same range of efficacy as barbiturates, covering some partial seizures and a porion of generalized seizures.
Coverage of the Generalized Seizures pipeline on the basis of route of administration and molecule type.
FDA approved for adjunctive treatment of partial seizures--widely used for generalized seizures, Lennox-Gastault syndrome and infantile spasms
In 1997, she woke up in the hospital after having three generalized seizures that occurred during sleep.
About FYCOMPA FYCOMPA (perampanel) is indicated as adjunctive therapy for the treatment of partial-onset seizures with or without secondarily generalized seizures and primary generalized tonic-clonic seizures in patients with epilepsy 12 years of age and older.
Epilepsy is broadly categorized by seizure type, with partial-onset seizures accounting for approximately 60% of epilepsy cases and generalized seizures accounting for approximately 40%.
Fewer than 25% had a history of generalized seizures.
Global Markets Direct's, 'Generalized Seizures - Pipeline Review, H2 2011', provides an overview of the Generalized Seizures therapeutic pipeline.
Generalized seizures account for approximately 40% of all epilepsy, and PGTC seizures are one of the most common and severe forms of generalized seizures that frequently lead to morbidity and mortality.
Headquarters: Tokyo, CEO: Haruo Naito, "Eisai") announced today that it has presented the results from a Phase III clinical study (Study 332) of its in-house developed antiepileptic drug (AED) Fycompa (perampanel) in patients with primary generalized tonic-clonic (PGTC) seizures, one of the most severe forms of generalized seizures.
It is indicated for adjunctive therapy in partial seizures, generalized seizures of Lennox-Gastaut syndrome, and primary generalized tonic-clonic seizures in adults and pediatric patients (greater than or equal to 2 years) as well as for conversion to monotherapy in adults with partial seizures who are receiving treatment with carbamazepine, phenytoin, phenobarbital, primidone, or valproate.

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