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general paresis

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paresis /pa·re·sis/ (pah-re´sis) slight or incomplete paralysis.
general paresis  paralytic dementia; a form of neurosyphilis in which chronic meningoencephalitis causes gradual loss of cortical function, progressive dementia, and generalized paralysis.

general paresis
n.
A brain disease occurring as a late consequence of syphilis, characterized by dementia, progressive muscular weakness, and paralysis. Also called Bayle's disease, paralytic dementia.

General paresis
A form of neurosyphilis in which the patient's personality, as well as his or her control of movement, is affected. The patient may develop convulsions or partial paralysis.
Mentioned in: Syphilis

general paresis
Etymology: L, genus, kind; Gk, paralysis
a neurologic disorder that results from chronic syphilitic infection. It is characterized by degeneration of the cortical neurons; progressive dementia, tremor, and speech disturbances; muscular weakness; and ultimately generalized paralysis. It is often accompanied by periods of exultation and delusions of grandeur. Treatment usually consists of large doses of penicillin, without which the outcomes are almost invariably progressive deterioration and death. Also called paretic dementia, syphilitic meningoencephalitis.

paresis [pah-re´sis, par´ĕ-sis]
slight or incomplete paralysis. adj., adj paret´ic.
general paresis chronic meningoencephalitis from a syphilitic infection that is causing gradual loss of cortical function, resulting in progressive dementia and generalized paralysis; this may occur 10 to 20 years after an initial infection of syphilis in untreated individuals. Called also Bayle's disease and dementia paralytica.

general paresis
Neurology A symptom of late tertiary syphilis 10+ yrs after the initial infection, caused by chronic meningoencephalitis resulting in progressive dementia and generalized paralysis. See Syphilis.


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Among their cases are a comparison two cases of 19th-century general paresis in Guy de Maupassant and Friedrich Nietzsche, substance abuse versus epilepsy in Edgar Allan Poe, Immanuel Kant's evolution from a personality disorder to a dementia, bipolar disorder as an explanation of Van Gogh's night, the terminal illness and last compositions of Maurice Ravel, Georg Friedrich Handel's strokes, and music and brain in Gershwin and Shebalin.
14) Common MRI findings in neurosyphilis patients with general paresis (personality [paranoia, carelessness in appearance]; affect [labile]; reflexes [hyperactive]; eye [Argyll Robertson pupils]; sensorium [hallucinations, illusions, delusions]; intellect [decreased recent memory, judgment, insight]; and speech [slurred]) include dilated ventricles and either increased signal or atrophy of the medial temporal lobes.
 
 
 
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