Given the gene-environment interaction
identified, we performed genotype stratified analyses in the combined sample (discovery and replication) as well as additional explorative analyses assessing the robustness of the observed [PM.
The literature surrounding specific gene-environment interactions
in the area of alcohol use has developed largely independently of the latent gene-environment interaction
literature reviewed above.
Detecting, characterizing, and interpreting gene-gene and gene-environment interactions
as risk factors for alcoholism is an important first step in a systems genetics approach that combines genomimics (2) and proteomics (3) data with methods to understand how biological processes work together to determine human health.
We then controlled the false discovery rate (FDR) for the gene-environment interaction
terms at q < 0.
Using twin studies conducted in Finland and other countries, researchers have analyzed the specific genetic and environmental influences as well as the gene-environment interactions
that shape drinking behavior in adolescence.
in developmental psychopathology.
Longitudinal studies of gene-environment interaction
in common diseases--good value for money?
BACKGROUND: Mechanisms whereby gene-environment interactions
mediate chronic, progressive neurodegenerative processes in Parkinson's disease (PD)--the second most common neurodegenerative disease--remain elusive.
The rest of the book is more appropriate for researchers and clinicians, with sections on general concepts of gene-environment interaction
in child development, and disorder-based examples of the interaction of genetic and environmental factors over time.
Individual susceptibility and gene-environment interaction
Interestingly, this gene-environment interaction
appeared to be especially important for male participants and not female children in the sample.
This finding appears to be the first example of gene-environment interaction
in autism," said senior author Irva Hertz-Picciotto.