Molecular biologists, botanists, crop scientists, and other researchers review the current status of the theory of gene silencing
and its application in plants.
Although Xist s regulation has been investigated intensively, less is known about the actual mechanisms underlying the process of chromosome-wide gene silencing
that it induces.
Controversial gene silencing
, also known as RNA interference (RNAi), was recently introduced with FDA approval for two new crops: apples that resist browning and potatoes that produce less acrylamide.
M2 PHARMA-August 9, 2013-Regen BioPharma Inc licenses cancer gene silencing
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M2 EQUITYBITES-August 9, 2013-Regen BioPharma Inc licenses cancer gene silencing
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The researchers investigated using nanoparticles to deliver double-stranded ribonucleic acid, dsRNA -- a molecule capable of specifically triggering gene silencing
-- into mosquito larvae through their food.
One of the key means by which cells achieve this control is by "RNA interference," a form of gene silencing
where small pieces of RNA, called micro RNAs, obstruct the production of specific proteins by interacting with their genetic code.
Scientists will use gene silencing
to discover plant genes that play a role in orchestrating defense responses to P.
Research leader Samuel Gunderson, an associate professor in the Department of Molecular Biology and Biochemistry at Rutgers, claims that his team have developed highly efficient gene silencing
agents that function via a novel mechanism of action.
Johnston, IA) has patented methods of controlling gene silencing
using site-specific recombination.
Epigenetics refers to the study of gene silencing
and non-Mendelian inheritance of traits.
, or RNA interference (RNAi) uses target-specific sequences of short interfering RNA molecules (siRNA molecules) to knock-down, or "silence" targeted genes to infer their function.