Gene dosage effect | definition of gene dosage effect by Medical dictionary
gene dosage effect
gene dos·age ef·fect
in codominant alleles, the more or less linear relationship between the phenotypic value and the number of genes of one type substituted by another type.
References in periodicals archive
We found a gene dosage effect
, the more unfavourable variations a woman has, the greater her ovarian cancer risk and the shorter her survival time," said senior author Xifeng Wu, M.
Proteolipid protein gene dosage effect
in Pelizaeus-Merzbacher disease.
Although mutations within the PMP22 gene have been identified in some cases of CMT1A and HNPP, a gene dosage effect
has been proposed as the principal underlying pathomechanism for development of CMT1A and HNPP (9-11).