Until now, as far as we are aware, there have been no reports on the regulative effects of EO from RA on delayed gastric emptying, gastrointestinal hormone
and corticotropin-releasing factor (CRF) abnormalities induced by restraint stress stimulation in animals and on the mechanism of action of the EO.
Our findings suggest that it may be useful for colon cancer treatment, as well as potential colon cancer suppression in cells that respond to the gastrointestinal hormone
The keyword constipation was crossreferenced with the following terms: circulating gastrointestinal hormones
, gastrin, cholycystokinin, secretin, motilin, neurotensin, vasoactive intestinal polypeptide, pancreatic polypeptides, glucagon, histamine, serotonin, norepinephrine, acetyicholine, gastric inhibitory peptide, prostaglandins, noncholinergic nonadrenergic peptides, endorphins, enkephalines, autonomic nervous system, sympathetic, and parasympathetic.
Synergy's lead proprietary drug candidate plecanatide is a synthetic analog of the human gastrointestinal hormone
uroguanylin, and functions by activating the guanylate cyclase C receptor on epithelial cells of the GI tract.
The discovery provides new insight into the metabolic role of a gastrointestinal hormone
found in the early 1980s.
5,118,666) covering the gastrointestinal hormone
, insulinotropin, related compounds and their use as treatment for Type II diabetes.
Tso claimed that their research shows apoA-IV to behave similar to an incretin-a gastrointestinal hormone
causing an increased release of insulin after eating to combat the onset of elevated blood glucose.
ORMD-0901 is a glucagon-like peptide-1 analog, a gastrointestinal hormone
that stimulates the secretion of insulin from the pancreas.
Given that many patients with diabetes significantly improve immediately after bariatric surgery, even before weight loss occurs, it is possible that improved insulin resistance might be independent of weight loss and could result from changes in gastrointestinal hormones
and regulatory peptides.