gastrin-releasing peptide


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gastrin-releasing peptide

a 27-amino acid linear neuropeptide, structurally and functionally related to bombesin, that mediates neural release of antral gastrin, causes bronchoconstriction and respiratory tract vasodilation, stimulates growth and mitogenesis of cells in culture, and may act as an excitatory neurotransmitter of enteric interneurons.
References in periodicals archive ?
Source ([dagger]) Dilution Chromogranin M M869 Dako 1:2500 Insulin P 299-230 Cambridge 1:100 Glucagon P A565 Dako 1:10 000 Gastrin P 1537 Immunotech 1:2000 Somatostatin P A566 Dako 1:3000 GRP P A429 Dako 1:1000 * M indicates monoclonal antibody; P, polyclonal antibody; and GRP, gastrin-releasing peptide.
Known as gastrin-releasing peptide receptor, or GRPR, the gene is not typically active in the lungs of nonsmokers, Shriver says.
The major new classes of drugs include SGLT-2 inhibitors, 11 HSD inhibitors, CCR2 antagonists, selective inhibitors of fructose 1,6-bisphosphatase, immune modulators, cortisol synthesis inhibitors, interleukin-1 antagonists, Gastrin-Releasing Peptide (GRP) receptor agonists, GPR 119 agonists, TLR-4 receptor agonists, FXR antagonists and antisense drugs targeting glucagon receptors.