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gastrin

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gastrin /gas·trin/ (gas´trin) a polypeptide hormone secreted by certain cells of the pyloric glands, which strongly stimulates secretion of gastric acid and pepsin, and weakly stimulates secretion of pancreatic enzymes and gallbladder contraction.
gas·trin (gstrn)
n.
Any of the hormones secreted in the pyloric-antral mucosa of the stomach and that stimulate secretion of the parietal cells.

Gastrin
A hormone secreted in the stomach that is involved in the production of gastric acid. Overproduction of gastric acid contributes to peptic ulcer formation.
Mentioned in: Gastrinoma, Ulcer Surgery

gastrin
[gas′trin]
Etymology: Gk, gaster, stomach
a polypeptide hormone, secreted by the pylorus, that stimulates the flow of gastric juice and contributes to the stimulus for bile and pancreatic enzyme secretion. Normal findings of blood levels of gastrin are less than 200 pg/mL.

gastrin,
n a digestive hormone produced in the antral part of the stomach that stimulates production of hydro-chloric acid in the gastric glands.

gastrin
a polypeptide hormone secreted by certain cells of the pylorus, which strongly stimulates secretion of gastric acid and pepsinogen, and weakly stimulates secretion of pancreatic enzymes and gallbladder contraction.

gastrin assay
plasma levels are elevated in gastrointestinal disease and other systemic diseases.


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? Mentioned in ? References in periodicals archive
 
Six of the mice lacking gastrin developed stomach tumors at 12 months of age, but none of normal mice did, the researchers report in the March 31 Oncogene.
Aphton's anti-gastrin targeted therapy induces antibodies in patients that bind to both gastrin 17 and gly-gastrin and remove them from circulation before they can bind to the cancer cell and initiate cell growth.
They secrete a substance called gastrin that causes the stomach to produce too much acid, which in turn causes the stomach and duodenal ulcers (peptic ulcers).
 
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