ganglionic blockade

blockade /block·ade/ (blok-ād´)

1. the blocking of the effect of a hormone or neurotransmitter at a cell-surface receptor by a pharmacologic antagonist bound to the receptor.

2. in histochemistry, a chemical reaction that modifies certain chemical groups and blocks a specific staining method.

3. regional anesthesia.

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adrenergic blockade  selective inhibition of the response to sympathetic impulses transmitted by epinephrine or norepinephrine at alpha or beta receptor sites of an effector organ or postganglionic adrenergic neuron.

cholinergic blockade  selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or the neuromuscular junction.

ganglionic blockade  inhibition by drugs of nerve impulse transmission at autonomic ganglionic synapses.

narcotic blockade  inhibition of the euphoric effects of narcotic drugs by the use of other drugs, such as methadone, in the treatment of addiction.

neuromuscular blockade  a failure in neuromuscular transmission that can be induced pharmacologically or may result from pathological disturbances at the myoneural junction.

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ganglionic blockade

n.

Inhibition of nerve impulse transmission at autonomic ganglionic synapses by drugs such as nicotine or hexamethonium.

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ganglionic blockade

[gang′glē·on′ik]

the blocking of nerve impulses at synapses of autonomic ganglia, usually by the administration of ganglionic blocking agents.

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ganglionic

pertaining to a ganglion.

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ganglionic blockade

inhibition by drugs of nerve impulse transmission at autonomic ganglionic synapses.

ganglionic blocking agent

see ganglion blocking.