gamma-hydroxybutyric acid

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γ-hydroxybutyric acid

Central nervous system depressant causing relaxation, loss of muscle tone and reduced inhibitions. Effects are enhanced when mixed with alcohol. Previously sold in health food stores as a performance-enhancing drug until banned by the FDA in 1990. Sometimes vernacularly termed date rape drug.
References in periodicals archive ?
GC-MS determination of gamma-hydroxybutyric acid (GHB) in blood.
Gamma-hydroxybutyric acid increases intracellular [Ca.
Effect of low doses of gamma-hydroxybutyric acid on serotonin, noradrenaline, and dopamine concentrations in rat brain areas.
Gallimberti L, Schifano F, Forza G, et al: Clinical efficacy of gamma-hydroxybutyric acid in treatment of opiate withdrawal.
Gallimberti L, Spella MR, Soncini CA, et al: Gamma-hydroxybutyric acid in the treatment of alcohol and eroine dependence.
Gamma-hydroxybutyric acid (GHB), an increasingly popular drug of illicit use, is a four carbon fatty acid endogenous metabolite of gamma amino butyric acid, a central nervous system depressant.
Galloway GP, Fredrick-Osborne SL, Seymour R, et al: Abuse and therapeutic potential of gamma-hydroxybutyric acid.