Also found in: Acronyms.


An enzyme that catalyzes the transfer of a γ-glutamyl group from a γ-glutamyl peptide (usually glutathione) to another peptide, certain amino acids, or water; a deficiency of this enzyme will result in glutathionuria.

gamma-glutamyltransferase (GGT)

an enzyme that appears in the serum of patients with several types of liver or gallbladder disorders, including drug hepatotoxicity, biliary tract obstruction, alcohol-induced liver disease, and liver carcinoma. Normal adult (after 45 years of age) GGT blood levels are 8 to 38 U/L.
References in periodicals archive ?
Association between serum gamma-glutamyltransferase level and prehypertension among US adults.
2006) Three-year increase of gamma-glutamyltransferase level and development of type 2 diabetes in middle-aged men and women: the D.
Validity of carbohydrate-deficient transferrin (%CDT), gamma-glutamyltransferase (gamma-GT) and mean corpuscular erythrocyte volume (MCV) as biomarkers for chronic alcohol abuse: a study in patients with alcohol dependence and liver disorders of non-alcoholic and alcoholic origin.
Gamma-glutamyltransferase and alkaline phosphatase activities compared in serum of normal children and children with liver disease.
Effect of troglitazone on serum gamma-glutamyltransferase activity and plasma t-PA/PAI-1 complex in type 2 diabetic patients.
A strong secular trend in serum gamma-glutamyltransferase from 1996 to 2003 among South Korean men.
0 mg/kg, with symptoms improving after a dose reduction, and keratitis (n=1) and gamma-glutamyltransferase increase (n=1), both reported at 1.
Vorarlberg Health Monitoring and Promotion Program Study Group: gamma-glutamyltransferase as a risk factor for cardiovascular disease mortality: an epidemiological investigation in a cohort of 163,944 Austrian adults.
ACERMANN, K; AND MANN, K Sex differences of carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume in alcohol-dependent patients.
Relationships between serum triglycerides and gamma-glutamyltransferase among shift and day workers.
1) regarding a strong interaction between serum gamma-glutamyltransferase (GGT) activity and body mass index (BMI) and their effect on the risk of prevalent diabetes.

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