gamma-butyrolactone


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γ-butyrolactone

Industrial solvent and purported health additive. Precursor in the synthesis of γ-hydroxybutyric acid.

gamma-butyrolactone

(găm′ə-byo͞o′tə-rə-lăk′tōn′)
n. Abbr. GBL
A chemical that has many industrial uses, especially as a solvent. It is a chemical precursor to gamma-hydroxybutyrate and is ingested illegally for its euphoriant and sedative effects.

gam·ma-bu·ty·ro·lac·tone

(GBL) (gam'ă-byū'tir-ō-lak'tōn)
An industrial and household solvent that is readily metabolized after oral ingestion to gamma-hydroxybutyrate (GHB). Like GHB, it is marketed illicitly as a euphoriant, appetite suppressant, antidepressant, and sleep aid. It is more potent than GHB and has both a more rapid onset and a longer duration of action, but its pharmacologic and toxic properties are essentially the same: nausea, bradycardia, and central nervous system depression ranging from drowsiness and confusion to seizures, coma, and death. Dependency and severe withdrawal symptoms have been reported.
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References in periodicals archive ?
Pentobarbital for severe gamma-butyrolactone withdrawal.
31 Gamma-Butyrolactone & Derivatives Solvents Demand 129
Police said a postmortem has yet to be held but added: "We believe that controlled substance gamma-butyrolactone, or GBL, may have been used as a drug at the gathering at the address.
The study Gamma-butyrolactone (gamma-butyrolactone(GBL)) (CAS 96-48-0) Market Research Report presents an overview of the Gamma-butyrolactone market globally and regionally by contemplating and analyzing its parameters.
Succinic acid yields derivatives such as 1,4-butanediol (BDO), gamma-butyrolactone (GBL), and tetrahydrofuran (THF), which have high potential for use as solvents and fibers.
Butanediol is used as an intermediate in the production of various downstream chemicals, including gamma-butyrolactone, tetrahydrofuran (THF), polytetrahydrofuran (PolyTHF(R)) and N-methyl, N-vinyl, and polyvinylpyrrolidone.
20, 1996--Lonza SpA, Milan, Italy and Akzo Nobel, The Netherlands, have signed a letter of intent on a joint feasibility study for setting up a 60/40 joint venture for the production of N-Methylpyrrolidone (NMP) and related intermediates including Gamma-butyrolactone (GBL).
has scaled up its hydrogenation catalyst technology under license from DuPont and converted multi-ton quantities of bio-succinic acid into 100% bio-based 1,4-butanediol (1,4-BDO), tetrahydrofuran (THF) and gamma-butyrolactone (GBL).
GBL, or Gamma-Butyrolactone, is used by some partygoers to achieve a legal high.

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