gamma knife

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gamma Knife

a minimally invasive radiosurgical system used in the treatment of benign and malignant intracranial neoplasms and arteriovenous malformations.
See also: radiosurgery.

Gamma Knife is a registered trademark of Elekta Radiosurgery of Atlanta, Georgia. The system was developed in the late 1960s by Lars Leksell and Borge Larsson of Sweden. As a preliminary to use of the Gamma Knife, the lesion to be ablated is precisely located by imaging techniques such as MRI, CT, PET, and angiography. Beams of gamma rays from 200 cobalt-60 sources are then directed by a computer so that they converge on the lesion. A series of exposures are made during a period of about 1 hour. Lesions larger than about 3 cm cannot be treated. The mechanism is bulky and costly, but the procedure has shown a success rate of about 85% in the treatment of arteriovenous malformations and 50-95% percent for neoplasms. Besides avoiding the risks and complications of open surgery, the Gamma Knife permits treatment of lesions the location of which prohibits any attempt at surgical removal. In addition, patient discomfort is minimal and most patients remain in the hospital for only 1 night. Many return home, or even to work, on the day of treatment. The Gamma Knife has demonstrated limited usefulness in the treatment of other disorders, such as tumors of the eye and the pituitary gland, trigeminal neuralgia, epilepsy, parkinsonism, and other movement disorders.

Gamma Knife

A trademark for a radiologic nonsurgical device used in stereotactic radiosurgery.

gamma knife

an apparatus for precisely aimed intersecting beams of gamma rays that delivers radiation therapies as treatment for intracranial lesions, either tumors or vascular anomalies. It is used in stereotactic radiosurgery.

gamma knife

Radiation oncology An RT device that provides 201 stereotactically focused beams of γ radiation from 60Co that destroys intracranial targets; the GK and linear accelerators can be adapted to irradiate localized regions of the brain Indications AV malformations, meningiomas, acoustic neuromas, pituitary adenomas, craniopharyngiomas, 1º and 2º tumors

Gamma knife

A surgical tool that focuses beams of radiation at the head, which converge in the brain to form a lesion.
Mentioned in: Brain Tumor, Psychosurgery

Gam·ma Knife

(gamă nīf)
Minimally invasive radiosurgical system used to treat benign and malignant intracranial neoplasms and arteriovenous malformations. [Gamma Knife is a registered trademark of Elekta Radiosurgery of Atlanta, Georgia.]
References in periodicals archive ?
Currently installed and in clinical operation at Hypital la Timone (Timone University Hospital) in Marseille, France, the first patients were successfully treated with Leksell Gamma Knife Perfexion in mid-July.
Lunsford says Leksell Gamma Knife Perfexion is a robust, reliable and extremely versatile radiosurgical device.
UPMC has partnered with Elekta since the first 201-source Gamma Knife - the fifth worldwide - was installed in Pittsburgh in 1987," says L.
8% share of the global Gamma Knife market in 2014 and is expected to further gain share at a comparatively high CAGR of 7% during the forecast period.
The Gamma Knife Center at Sacred Heart Medical Center is the only location between Portland and Sacramento using this high-tech neurosurgical tool.
Once completed, the images are transferred via ethernet to the Gamma Knife Treatment Planning computer where a team comprising the neurosurgeon, radiation oncologist, and a radiation physicist carries out radiosurgery dose planning.
The cumulative risks of recurrence requiring surgical salvage and/or late radiation complication is too high in my opinion," to use the Gamma Knife, San Francisco neurosurgeon Robert K.
The Gamma Knife Centre provides a high quality radiosurgical service for National Health Service (NHS) and private patients, and is a partnership between the NHNN, part of the University College London Hospitals (UCLH) NHS Foundation Trust and Medical Equipment Solutions Limited.
Hospital officials said they estimate 200 to 300 patients will get the Gamma Knife treatment in its first year of operation.
is a Peruvian physician, trained as a neurosurgeon in the United States, Board Certified and with ample experience in Gamma Knife radiosurgery, having performed over 400 Gamma Knife procedures.
Giannotta said that the gamma knife was designed to treat AVMs of the brain, and using the device to treat a facial AVM is much more rare.