gallbladder carcinoma

gallbladder carcinoma

a malignant neoplasm of the bile reservoir, characterized by anorexia, nausea, vomiting, weight loss, progressively worsening right upper quadrant pain, and eventually jaundice. Tumors of the gallbladder are predominantly adenocarcinomas. Often associated with biliary calculi and chronic cholecystitis, they are three to four times more common in women than in men and rarely occur before 40 years of age. Physical examination reveals an enlarged gallbladder in about half of the cases. Ultrasound or radiographic tests may aid in making a diagnosis. Complete removal of the gallbladder may sometimes be curative, but partial hepatectomy may be required because the tumor typically infiltrates the liver and ducts. Palliative surgery is often needed. Radiotherapy may be palliative. Chemotherapy is usually ineffective.
enlarge picture
Gallbladder carcinoma
References in periodicals archive ?
Perforations due to trauma, iatrogenic causes and gallbladder carcinoma were not included in this study.
Pre- and intra-operative diagnosis is difficult, and it often mimics a gallbladder carcinoma (GBC).
Expression of p16 protein in gallbladder carcinoma and its precancerous conditions.
Operation Details: All patients received surgical treatment under general anesthesia, including pancreaticoduodenectomy in 17 cases, hilarcholangiocarcinoma radical resection in 14 cases (combined with right hemihepatectomy in 5 cases; with the left hemihepatectomy in 4 cases; with hepatic segment resection in 5 cases), gallbladder carcinoma radical resection in 5 cases, cholangiojejunostomy in 5 cases, no patient died during the operation.
Porcelain gallbladder is not associated with gallbladder carcinoma.
Many studies have examined the synergistic effect of autophagy and 5-FU in colorectal cancer, hepatocellular carcinoma (HCC), pancreatic adenocarcinoma, esophageal cancer, gallbladder carcinoma (GBC), and gastric cancer [Table 1]; some hold great promise and are currently being investigated within the context of phase I and phase II clinical trials [Table 2].
Open versus laparoscopic cholecystectomy for gallbladder carcinoma.
Gallbladder carcinoma manifesting as acute cholecystitis: clinical and computed tomographic features.
The following describes the occurrence of Streptococcus bovis bacteremia in a patient with a coexisting gallbladder carcinoma.
The most common malignancy in this study was pancreatic adenocarcinoma (n=24), followed by cholangiocarcinoma (n=11), gallbladder carcinoma (n=4), biliary compression by malignant nodes in the porta hepatis (n=4), and gastric (n=3), duodenal (n=2) and ampullary carcinoma (n=2).
Primary gallbladder carcinoma is a malignant neoplasm with an incidence of 1.
On the other hand, imaging studies alone are insufficiently specific to exclude the possibility of gallbladder carcinoma or premalignant adenomas.