galectin


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galectin

(gă-lek′tĭn)
Any of a family of galactosidase-binding proteins. Galectin-3 is a potential biomarker of myocardial fibrosis in patients with heart failure.
References in periodicals archive ?
D, chairman, Galecto, added : "Partnering with Bristol-Myers Squibb validates what we have created in Galecto, and will allow us to advance TD139 and our portfolio of other galectin modulators for several important human conditions.
Galectin Therapeutics is currently conducting a Phase 1 clinical trial to evaluate the safety, tolerability and exploratory biomarkers for efficacy for single and multiple doses of GR-MD-02 over four weekly doses of GR-MD-02 treatment in patients with fatty liver disease with advanced fibrosis.
In addition, excessive amounts of the most studied galectin, Galectin-3, makes cancer more aggressive.
Galectin 3 aggravates joint inflammation and destruction in antigen-induced arthritis.
Background and Design: In view of the evolving knowledge about the presence of the potent proinflammatory galectin-3, a member of the galectin family, in the cells (mainly T-lymphocytes) playing a key role in the inflammation process.
We, therefore, explored the diversity of the galectin gene in natural populations of P.
a developer of therapeutics that target Galectin receptors to treat cancer and fibrosis, has granted PROCAPS S.
Studies were conducted to understand the potential role of galectin-3 and dietary galectin inhibitors in tumour spread and prevention respectively.
Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting.
Contributors from all over the world address such topics as galectin inhibitors, angiogenesis and chemoresistance.
The diverse kinds of galectin suggest variety in their biological roles.