galanthamine


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Related to galanthamine: Galantamine, Galantamine hydrobromide

ga·lan·tha·mine

(gă-lan'thă-mēn),
An alkaloid derived from Caucasian snowdrops (a white flower of early spring) Galanthus woronowii (family Amaryllidaceae); from Narcissus spp. An alkaloid with anticholinesterase properties; enjoys use in Eastern Europe.

galanthamine (g·lanˑ·th·mēn),

n Latin name:
Galanthus nivalis; part used: bulbs; uses: polio-induced paralysis, myasthenia gravis, Alzheimer's disease; precautions: pregnancy, lactation, children; patients exposed to organophosphate fertilizers; can cause dizziness, confusion, insomnia, nausea, stomach cramps, diarrhea.
References in periodicals archive ?
Despite being 23 times less potent than galanthamine against AChE, upon a molar basis comparison, angustidine (2) was 28 times more potent as an inhibitor of BChE compared to galanthamine.
Drug application: Substances used in this experiment included TDE (dissolved in ethanol), atropine, ACh and galanthamine (dissolved in dd[H.
Bulbs grown at 1,400ft in the Black Mountains produce twice as much galanthamine as those planted in Pembrokeshire at sea level.
In the primary outcome measure, which was the time to relapse, galanthamine was significantly inferior to placebo: 39 days with the drug, compared with 63 days for placebo.
In the United States, clinical trials of the new galanthamine derivatives may begin within a year, Kosley says.
Acetylthiocholine iodide, acetylcholinesterase from electric eel (AChE), 5,5'-dithiobis[2-nitrobenzoic acid] (DTNB), butyryl-cholinesterase from equine serum (BChE), S-butyrylthiocholine chloride, physostigmine and galanthamine were purchased from Sigma Chemicals (St.
The Company's new products launched in 2010 were Galanthamine Hydromide, Hydroxycamptothecin, Tanshinone IIA, Cow-bezoar Detoxicating table, Ganhai Stomach Recovery capsule, Camptothecine, VC Honeysuckle-fructus Forsythiae table and compound Salvia Root.
And the common daffodil contains galanthamine, used in the treatment of Alzheimer's disease.
Therefore, the large numbers of structurally diverse Amaryllidaceae alkaloids were chemically classified into several types based on their chemical skeleton such as the lycorine, crinine, homolycorine, galanthamine, montanine, pancratistatin, buflavine and cherylline-type (Unver 2007).
Dr Ainsworth is also a director of Powys-based company Alzeim, which is producing the registered drug Galanthamine from daffodils which slows the progression of the condition Alzheimer's.
Research being carried out by new company Alzeim Ltd could result in the production of a sustainable supply of galanthamine.
Comparison with tacrine and galanthamine on oxidative stress and mitochondrial impairment.