5 % of patients who had received continuous galantamine
treatment were still at home compared to 65 % of patients treated for 24 to 36 months, 48 % of patients treated for 12 to 24 months and 54 % of patients treated for 12 months or less respectively.
In a 6-month open-label extension in which the drug was given to all patients, benefits were sustained in those who had originally been in the galantamine
(Reminyl): Used for more severe forms of dementia, the side-effect profile is similar as above.
has some physical and psychological side effects, it should be used with discretion.
Donepezil, along with galantamine
and rivastigmine, has been commonly prescribed for treatment of Alzheimer's disease.
Hilmas worked as a physiologist and principal investigator for the US Army Medical Research Institute of Chemical Defense, investigating the efficacy of two dietary ingredients, galantamine
Gold served as the Compound Development Team Leader for Galantamine
, an Alzheimer's drug, culminating in FDA approval of Galantamine
CR (Razadyne ER).
Professor Peter Nordstrom, of Umea University, Umea, Sweden, and colleagues reviewed records on 7,073 Alzheimer's patients taking cholinesterase inhibitors (ChEIs), such as donepezil, rivastigmine and galantamine
, which are used for treating mild to moderate Alzheimer's disease.
AChE from Electrophorus electricus, BChE from equine serum and galantamine
hydrobromide were purchased from Sigma (St.
is another cholinesterase inhibitor approved for patients with mild to moderate Alzheimer's disease, and it has dosing options of 6 mg, 8 mg, or 12 mg b.
The Alzeim firm, from Talgarth near Brecon, Powys, farms daffodils in the Black Mountains for a compound called galantamine
, which scientists believe can slow the progress of the Alzheimer's.
Nice confirmed that it was extending previous recommendations for the use of three drugs - Donepezil (Aricept, Eisai/Pfizer), galantamine
(Reminyl, Shire) and rivastigmine (Exelon, Novartis) - to include mild, as well as moderate Alzheimer's disease.