galactosylceramide

ga·lac·to·syl·cer·a·mide

(gă-lak'tō-sil-ser'ă-mīd),
A sphingolipid that accumulates in people with Krabbe disease.

galactosylceramide

References in periodicals archive ?
The invention of Galactosylceramide was the result of intensive efforts by AUBMC's Chief of the Pediatric Neurology Division and Director of Neurogenetics Program and Special Kids Clinic Rose-Mary Boustany, and her team.
It is an autosomal recessive sphingolipidosis caused by deficient activity of the lysosomal enzyme galactosylceramide beta-galactosidase (GALC) which degrades galactosylceramide, a main component of myelin, and other terminal beta-galactose-containing sphingolipids, including psychosine (galactosylsphingosine).
The virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal cell line.
A microwave-mediated saponification of galactosylceramide and galactosylceramide 13-sulfate and identification of their lysocom pounds by delayed extraction matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
Infection of colonic epithelial cell lines by Type I human immunodeficiency virus associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.
KineMed aims to develop lipid kinetic biomarkers, including the dynamics of cholesterol, phospholipids and galactosylceramide in the brain, as well as the synthesis of plasma 24-hydroxy cholesterol.
2008) CLN3p impacts galactosylceramide transport, raft morphology, and lipid content.
Galactosylceramide is galactosylated by a galactosyltransferase (UDP-galactose:ceramide galactosyltransferase) found exclusively in the ER, whereas the UDP-Gal transporter has mainly a Golgi localization.
2000) Biochemistry and neuropathology of mice doubly deficient in synthesis and degradation of galactosylceramide.