galactocerebroside


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galactocerebroside

/ga·lac·to·ce·re·bro·side/ (gah-lak″to-sĕ-re´bro-sīd) any of the cerebrosides in which the head group is galactose; they are abundant in the cell membranes of nervous tissue.

galactocerebroside

a glycosphingolipid with a galactose unit. Called also galactolipid. See globoid cell leukodystrophy.
References in periodicals archive ?
Basically three lipid coatings are used for coating the CHITIns, which include (a) (PC) phosphatidylcholine to prepare PCCHITIns (b) (3L) with the mixed lipid composition, phosphatidylcholine: cholesterol (Chol): galactocerebroside (GalC) to prepare (3LCHITIns), and (c) (4L) with the mixed lipid composition, phosphatidylcholine: cholesterol: galactocerebroside: phosphatidylethanolamine (PE) to prepare (4LCHITIns).
2] Nonstandard abbreviations: PKU, phenylketonuria; BIA, bacterial inhibition assay; MS/MS, tandem mass spectrometry; LSD, lysosomal storage disorder; MPS II, mucopolysaccharidosis type II; HSCT, hematopoietic stem cell transplantation; CNS, central nervous system; ASM, acid sphingomyelinase deficiency; GAA, acid alpha glucosidase; ESI, electrospray ionization; GALC, galactocerebroside [beta]-galactosidase.
Antibodies to gangliosides and galactocerebroside in patients with Guillain-Barre syndrome with preceding Campylobacter jejuni and other identified infections.
Specifically, the straw-shaped microtubules, measuring some 120 nanometers in diameter, are made of the sugar-based lipid galactocerebroside.
A In order for full-blown autoimmune demyelination to take place in guinea pigs, we think that two components of the myelin sheath must be seen by the immune system: myelin basic protein (MBP), which is the major causal antigen in the animal disease, and a lipid in the sheath called galactocerebroside, or GC.
An adaptation of this method enabled direct analysis of galactocerebroside [beta]-galactosidase activity in DBS for the diagnosis of Krabbe disease (18).
The Einstein group theorized that injecting a preparation containing two components of myelin -- myelin basic protein and galactocerebroside -- might elicit a myelin-restoring immune response in guinea pigs with already established disease.
6] Nonstandard abbreviations: DBS, dried blood spot; ABC, acid [beta]-glucocerebrosidase; GLA, acid [alpha]-galactosidase A; GAA, lysosomal acid [alpha]-glucosidase; ASM, acid sphingomyelinase; GALC, galactocerebroside [beta]-galactosidase; PMN, polymorphonuclear leukocyte; CID, collision-induced dissociation; and RAAG, renal acid [alpha]-glucosidase.
We investigated whether MS/MS can be used to directly assay enzymes in dried blood spots, in this case, galactocerebroside [beta]-galactosidase (GALC; EC 3.
2]N, BN, C, cystine-derived, galactocerebroside, metal, dichalcogenide, Mo[S.
Niemann-Pick (1) and Krabbe (2-4) diseases are severe autosomal recessive diseases that are caused by a deficiency in the activity of the lysosomal enzymes acid sphingomyelinase (ASM) [4] and galactocerebroside [beta]-galactosidase (GCG), respectively.
Galactocerebrosides and sulfatides are major constituent lipids of myelin sheath.