gabapentin


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gabapentin

 [gab″ah-pen´tin]
an anticonvulsant chemically related to γ-aminobutyric acid, used in treatment of partial seizures; administered orally.

gabapentin

/gab·a·pen·tin/ (-pen´tin) an anticonvulsant related to γ (GABA), used in the treatment of partial seizures.

gabapentin

(găb′ə-pĕn′tn)
n.
An oral anticonvulsant chemically related to gamma-aminobutyric acid, C9H17NO2, used primarily in the treatment of focal seizures and neuralgia, especially after infection with herpes zoster.

gabapentin

[gab′äpen′tin]
an anticonvulsant chemically related to alpha-aminobutyric acid, used in treatment of partial seizures, administered orally.

gabapentin

Neurontin® Neurology An antiepileptic structural analogue of GABA, which binds to a poorly characterized brain receptor Indications Drug-refractory complex partial seizures, generalized seizures, with/without 2º generalization Adverse effects Vertigo, somnolence, headaches; it has little interaction with other agents. See Convulsion.

gabapentin

An analogue of the natural NEUROTRANSMITTER GABA used in the management of certain types or epilepsy. A brand name is Neurontin.

gabapentin

anticonvulsant agent with relatively few side-effects; used to treat epilepsy, and in neuropathic pain

gabapentin

(gab´əpen´tin),
n brand name: Neurontin;
drug class: an-ticonvulsant;
action: anticonvulsant action is unclear;
use: adjunctive therapy in adults with partial seizures.

Patient discussion about gabapentin

Q. I have heard of Gabapentin. It’s really useful for the treatment of acute depressed, manic states.Is it true… I have heard of Gabapentin. It’s really useful for the treatment of acute depressed, manic states and can it also be used to prevent future episodes of mania and depression? Is it true…

A. YES Kennedy,Earlier it was used for the treatment of people with depressed, manic and mixed states and was mainly given for the patients who did not respond to other medications. Now a days some patients are being prescribed gabapentin on a long term basis in an attempt to prevent future episodes. Its effectiveness as a long-term prophylactic agent is currently being investigated. Gabapentin is also increasingly used in pain clinics, headache clinics and clinics treating fibromyalgia. I hope my explanation is satisfactory to you.

More discussions about gabapentin
References in periodicals archive ?
Are the FDA and DEA currently investigating the rise in abuse of gabapentin and related overdose deaths?
While the quantity of gabapentin sold in Turkey in 2011 was 3,725,927 boxes, this number increased up to 4,621,100 boxes in 2014.
Conclusion: Preoperative use of pregabalin provides significantly prolonged postoperative analgesia compared to gabapentin after open cholecystectomy.
Gabapentin is approved by the Food and Drug Administration to treat epilepsy and pain related to nerve damage, called neuropathy.
The aim of this study was to compare the effect of gabapentin and pregabalin with the control group on the postoperative pain in patients scheduled for surgery under general anaesthesia.
Gabapentin compared with ketotifen had a better effect on improving itching in the age group of 30-60 years and in males.
Gabapentin in PTSD: a retrospective, clinical series of adjunctive therapy.
Pharmacologic treatment recommendations are often multimodal and, in people, include a combination of antidepressants, gabapentin or pregabalin, topical anesthetics, opioids, and tramadol.
During this study, The Institute is collaborating with XenoPort, a biopharmaceutical company, that will supply gabapentin enacarbil.
Objective: To evaluate the effects of oral gabapentin on early postoperative pain, nausea, and vomiting in patients undergoing LC.
The rate of treatment-related adverse events was higher in patients randomized to gabapentin than to women assigned to electroacupuncture, sham acupuncture, or placebo, Dr.
ii) Maximal Electroshock-Induced Seizure Test: The anticonvulsant activity of lamotrigine, gabapentin and topiramate was determined as their median effective dose (ED50 value in mg/kg) against maximal electroshock-induced seizures (0.