During this time, homotypic fusion of yeast vacuoles was also shown to proceed after SNARE complex disassembly (via treatment with excess yeast homologs of NSF and [alpha]-SNAP), indicating the need for a downstream fusogen
(Ungermann et al.
Scientists have known that the herpes virus fusogen does not act alone, requiring a complex of two other viral cell-entry proteins.
This unexpected result leads us to believe that this protein complex is not a fusogen itself but that it regulates the fusogen.
Pharmaceuticals has developed a new HIV fusion inhibitor that is currently in human clinical trials.
We have known that the herpes virus fusogen
does not act alone and that a complex of two other viral cell-entry proteins is always required.
was prepared by melting 1 g of polyethylene glycol 4000 (cat.