fusidic acid


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fu·sid·ic ac·id

(fyū-sid'ik as'id),
A fermentation product of Fusidium coccineum, a parasitic fungus on the plant Veronica; inhibits protein synthesis and the accumulation of ppGpp.
Synonym(s): ramycin

fusidic acid

A steroid antibiotic used in the form of sodium fusidate against penicillin-resistant (beta-lactamase-producing) staphylococci. It has no value against streptococci and is usually given in conjunction with another antibiotic such as FLUCLOXACILLIN. Brand names are Fucidin and Fucithalmic.

fusidic acid

A product used as an antibiotic agent in solution 1%. It is synthesized as sodium fusidate from the microorganism Fusidium coccineum. It is effective against gram-positive bacteria. It is used in the treatment of bacterial blepharoconjunctivitis, especially staphylococcal infection.

fusidic acid

a lipophilic steroid antibioitic, the product of Fusidium coccineum; mainly active against gram-positive bacteria.
References in periodicals archive ?
Investigation of the potential for mutational resistance to XF-73, Retapamulin, Mupirocin, Daptomycin, Fusidic acid & Vancomycin in MRSA isolates during a 55 passage study.
Transconjugants were selected on brain heart infusion medium containing vancomycin (32 [micro]g/mL) and fusidic acid (25 [micro]g/mL).
Although, generally, fluoroquinolones rarely show antagonism in combination with other antibiotics, our data seem to agree with several studies in which fluoroquinolones both Grampositive and Gram-negative bacteria, in combination with ertapenem, rifampin, fusidic acid and linezolid act antagonistically (Hosgor-Limoncu et al.
In the UK, commonly available topical antibiotics include fusidic acid and Chloramphenicol.
aureus strains was determined by disc diffusion method for penicillin G (10 UI), gentamicine (10 [micro]g), tobramycin (10 [micro]g), kanamycin (30 [micro]g), amikacin (30 [micro]g) erythromycin (15 [micro]g), spiramycin (10 [micro]g), lincomycin (10 [micro]g), la pristinamycin (15 [micro]g), la vancomycin (30 [micro]g), l'ofloxacin (5 [micro]g), tetracyclin (30 [micro]g), chloramphenicol (30 [micro]g), fosfomycin (50 [micro]g), fusidic acid (10 [micro]g), la bacitracine (8 [micro]g), nalidixic acid (30 [micro]g), noviobicine (30 [micro]g) (Bioanalyse, UK) and three antimicrobials such erythromycin, tetracycline, chloramphenicol were selected and confirmed by MIC (E-test) (Biomerieux, Marcy, l'Etoile, France) on Muller Hinton agar.
Both strains were resistant to trimethoprim, co-trimoxazole, erythromycin, mupirocin (low level) and fusidic acid (intrinsic resistance).
Treatment: GPs often prescribe a fusidic acid cream or if badly infected, fever or swollen lymph glands, then an oral antibiotic.
Fortunately, most isolates remain sensitive to vancomycin, clindamycin and fusidic acid.
Based on efficacy and resistance data, fusidic acid is the antibiotic of choice.
26) Fusidic acid (widely used in Europe but not available in the United States) was reportedly a very effective topical and parenteral therapy, (20,21,29) with currently reduced usefulness in Europe due to high levels of resistance from its widespread use as a monotherapy.
Postoperatively, she received intravenous flucloxacillin and oral fusidic acid for 1 week and orally for 5 weeks.