For each extract the furocoumarin
imperatorin was quantitatively characterized by FIPLC-DAD (Fig.
Dong quai, which is often taken for menstrual cramps, contains natural coumadin and furocoumarin
1 A), a dietary furocoumarin
, was wide spread and found not only in the medicinal plant such as Cnidium monnieri (L) cusson and Angelica dahurica (Fisch.
A clinical trial by Partonen (1998) demonstrated that administration of furocoumarin
psoralen inhibited hepatic melatonin metabolism to treat seasonal affective disorders in humans in Finland.
Molecular and genetic basis of furocoumarin
aurantium also contains a furocoumarin
(bergapten) that inhibits CYP3A4.
Beer, beef and mushrooms contain carcinogens such as hydrazine, furocoumarin
and ethyl carbamate.
Lime juice contains furocoumarin
, a lipid-soluble 8-methoxypsoralen.
Limes, as well as celery and parsley, contain furocoumarin
, an agent that makes skin more sensitive to the sun.
Consuming celery, mushrooms, roast beef, or beer would taint the blood with furocoumarin
, hydrazine, 2-amino-3-methylimidazo[4,5-f] quinoline, and ethyl carbamate--all known natural carcinogens.
Some Naturally Occurring And Synthetic Food Components, Furocoumarins
and Ultraviolet Radiation.
Compounds called furocoumarins
in grapefruit juice increase the bioavailabiity of several drugs by interfering with enzyme activity in the small intestine.