furazolidone

furazolidone /fu·ra·zol·i·done/ (fū″rah-zol´ĭ-dōn) an antibacterial and antiprotozoal effective against many gram-negative enteric organisms; used in the treatment of diarrhea and enteritis.

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furazolidone

[foo͡′rəzol′idōn]

an antibiotic with antibacterial and antiprotozoal activity.

indications It is prescribed for the treatment of diarrhea caused by susceptible bacterial or protozoal infections (e.g., Giardiasis, Vibrio) of the GI tract.

contraindications Known hypersensitivity to this drug prohibits its use. It is not given to children less than 1 month of age, and it is not used with drugs that are contraindicated with monoamine oxidase inhibitors. Foods high in tyramine and concurrent use of alcohol should be avoided.

adverse effects Among the more serious adverse effects are hemolytic anemia and fever, skin rash, and abdominal pain.

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furazolidone

a nitrofuran antibiotic, used as a local antibacterial and antiprotozoal. Used in poultry and swine as a feed additive to treat bacterial and protozoal intestinal infections. Calves fed low levels of furazolidone over long periods develop a leukopenia, petechial hemorrhages everywhere and are susceptible to infection. It is usually a sequel to prophylactic feeding of antibiotics. See also granulocytopenic calf disease.