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furanose |
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furanose /fu·ra·nose/ (fu´rah-nos) any sugar containing the four-carbon furan ring structure; it is a cyclic form that ketoses and aldoses may take in solution.
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The term "Locked Nucleic Acids" was coined by Exiqon to emphasize that the usual conformational freedom of the furanose ring in standard nucleosides is restricted in LNA(TM) due to a methylene linker connecting the 2'-O position to the 4'-C position. |
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furanose