furanocoumarin


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furanocoumarin

(fyūr-a-nō-kū-mah'rinz),
Member of a group of chemical compounds found in grapefruit, which includes bergamottin and 6'7'-dihydroxybergamottin. Inhibit CYP450 3A4, particularly in the GI tract.
See also: bergamottin.

furanocoumarin

naturally occurring photodynamic substances in plants and probably fungi. See also furocoumarin.
References in periodicals archive ?
Leaves and stalks of celery contain phenols, furanocoumarin, psoralen, bergapten, fully and xanthotoxin that their amount is changing from 12 to 50 mg/kg [13].
PAL is also known to be involved in the lignification process and as a key enzyme in phenylpropanoid biosynthetic pathway, which is the gateway to many plant secondary metabolites such as flavonoids pigments, furanocoumarin, isoflavonoid, phytoalexin, wound protectant hydroxycinnamic acid esters and aromatic compound in the plant defense system (Dixon et al.
Grapefruit contains the flavonoids, naringenin and furanocoumarin bergamottin--inhibitors of intestinal CYP3A4.
Role of furanocoumarin derivatives on grapefruit-mediated inhibition of human CYP3A4 activity.
AFG2), are furanocoumarin derivatives and potent liver carcinogens for
For the furanocoumarin type of compounds xanthotoxol (6) which is a simple furanocoumarin with the free hydroxyl group, is actually promoting the adipogenesis.
Explaining some of the most common hazardous food and drug combinations, Alder said that grapefruit contains a compound called furanocoumarin that prevents the enzymes in our intestine, responsible for keeping foreign substances out of our bodies, from working properly.
Xanthotoxol (6), is a hydroxylated furanocoumarin showed negligible activity of 30.
A high furanocoumarin content was detected in fruit and leaf and low furanocoumarin levels were found in bark and wood.
Chemical constituents of Prangos tschimganica; structure elucidation and absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity.
ents it GRAPEFRUIT contains active ingredients called furanocoumarins, which inhibit an enzyme in the intestines from doing its usual job of processing and detoxifying drugs.