Leaves and stalks of celery contain phenols, furanocoumarin
, psoralen, bergapten, fully and xanthotoxin that their amount is changing from 12 to 50 mg/kg .
PAL is also known to be involved in the lignification process and as a key enzyme in phenylpropanoid biosynthetic pathway, which is the gateway to many plant secondary metabolites such as flavonoids pigments, furanocoumarin
, isoflavonoid, phytoalexin, wound protectant hydroxycinnamic acid esters and aromatic compound in the plant defense system (Dixon et al.
Grapefruit contains the flavonoids, naringenin and furanocoumarin
bergamottin--inhibitors of intestinal CYP3A4.
Role of furanocoumarin
derivatives on grapefruit-mediated inhibition of human CYP3A4 activity.
AFG2), are furanocoumarin
derivatives and potent liver carcinogens for
A new furanocoumarin
glycoside from Carum montanum (Apiaceae).
For the furanocoumarin
type of compounds xanthotoxol (6) which is a simple furanocoumarin
with the free hydroxyl group, is actually promoting the adipogenesis.
Explaining some of the most common hazardous food and drug combinations, Alder said that grapefruit contains a compound called furanocoumarin
that prevents the enzymes in our intestine, responsible for keeping foreign substances out of our bodies, from working properly.
Xanthotoxol (6), is a hydroxylated furanocoumarin
showed negligible activity of 30.
A high furanocoumarin
content was detected in fruit and leaf and low furanocoumarin
levels were found in bark and wood.
Chemical constituents of Prangos tschimganica; structure elucidation and absolute configuration of coumarin and furanocoumarin
derivatives with anti-HIV activity.
ents it GRAPEFRUIT contains active ingredients called furanocoumarins
, which inhibit an enzyme in the intestines from doing its usual job of processing and detoxifying drugs.