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fumaric acid esters

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fumaric acid esters (fy·marˑ·ik aˑ·sid esˑ·terz),
n.pl Scientific names:
monoethyl fumarate, dimethyl fumarate; uses: psoriasis; precautions: can cause nephrotoxicity; partially reversible acute renal failure, osteomalacia, gastrointestinal dis-turbances, flushing, skin reactions, reversible elevated levels of transaminases, eosinophilia, and reversible lymphopenia. Also called
FAE.
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nbsp;therapy, consisting of a mixture of fumaric acid esters, referred to as BG00012, produced by Fumapharm AG, has been used in Europe as a treatment for psoriasis for decades.
Is an oral disease-modifying drug on the horizon? by Richert, John / Inside MS
FUMADERM, an oral product containing fumaric acid esters, was approved in Germany in 1994 where it is the leading prescription for oral systemic treatment of severe psoriasis.
Biogen Idec to Acquire Fumapharm AG; Consolidates Ownership of Oral ... by Business Wire
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