FUT2

(redirected from fucosyltransferase 2)

FUT2

A gene on chromosome 19q13.3 that encodes a Golgi membrane protein involved in synthesising an H-antigen precursor, which is required for the final step in synthesising soluble A and B antigens. FUT2 is one of two genes that encode galactoside 2-L-fucosyltransferase.
References in periodicals archive ?
6] Human genes: FUT2, fucosyltransferase 2 (secretor status included) (alias, galactoside 2-[alpha]-L-fucosyltransferase 2); FUT3, fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); MGAT5, mannosyl ([alpha]-1,6-)-glycoprotein [beta]-1,6-N-acetyl-glucosaminyltransferase.
Persons carrying [greater than or equal to] 1 functional FUT2 allele, and thus expressing [alpha]1,2 fucosyltransferase 2 (FucT-II), are termed secretor positive (secretors), and can express the A and B blood group antigens as well as H-type 1 and Lewis b ([Le.