fructose-1,6-bisphosphatase

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fructose-1,6-bisphosphatase /fruc·tose-1,6-bis·phos·pha·tase/ (bis-fos´fah-tās) an enzyme catalyzing part of the route of gluconeogenesis in the liver and kidneys; deficiency causes apnea, hyperventilation, hypoglycemia, ketosis, and lactic acidosis and can be fatal in the neonatal period.

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bifunctional enzyme fructose			MB07803 is Metabasis' product candidate for the treatment of type 2 diabetes that acts by inhibiting fructose-1,6-bisphosphatase (FBPase). METABASIS GETS GOOD RESULTS FROM MB07803 PHASE 2A TRIAL by Biotech Business MB07803 is designed to reduce glucose production in the liver by inhibiting the enzyme fructose-1,6-bisphosphatase (FBPase). Metabasis Therapeutics Announces First Quarter 2009 Financial Results by Business Wire The abstract, entitled "Pronounced Glucose Reduction In Poorly Controlled T2DM with MB07803, a Novel Fructose-1,6-bisphosphatase Inhibitor (FBPaseI) with Reduced Potential for Acid-Base Disturbances vs the 1st Generation FBPaseI CS-917" will be presented in poster format in the Clinical Therapeutics/New Technology-Pharmacologic Treatment of Diabetes or its Complications category. Metabasis Therapeutics Announces Late-Breaking Abstract on MB07803 ... by Business Wire			frottage frotteur frotteurism frounce frovatriptan frovatriptan succinate frozen frozen blood frozen pelvis frozen section frozen section method frozen sections frozen shoulder FRS fructo- fructofuranose fructokinase fructolysis fructooligosaccharide fructosamine fructosamine test fructose fructose intolerance fructose intolerance syndrome fructose test fructose-1,6-bisphosphatase fructosemia fructoside fructosuria fructosyl frugivorous fruit fruit & vegetable Fruit and Vegetables fruit bat fruit sugar Fruit Vegetable frusemide frustration FRV fry Frye Rule Fryette's Laws FSE FSF FSH FSH-RF FSH-RH FSH/LH-RH FSK FSP			fructose 1-phosphate aldolase fructose 1-phosphate aldolase Fructose 2,6-bisphosphatase Fructose 2,6-bisphosphatase Fructose 2,6-bisphosphatase Fructose 3-Phosphate Fructose 6-phosphate Fructose 6-phosphate Fructose 6-phosphate Fructose Bisphosphate Fructose bisphosphate aldolase Fructose bisphosphate aldolase Fructose bisphosphate aldolase Fructose intolerance Fructose intolerance Fructose intolerance fructose intolerance syndrome Fructose intoxication Fructose intoxication Fructose intoxication Fructose metabolism Fructose metabolism Fructose metabolism Fructose metabolism, inborn errors Fructose metabolism, inborn errors Fructose metabolism, inborn errors fructose test fructose tolerance test fructose tolerance test fructose tolerance test fructose-1,6-bisphosphatase Fructose-1-phosphate Fructose-1-Phosphate Aldolase Fructose-3-Phosphate Fructose-6-phosphate Fructose-bisphosphate aldolase Fructose-Glucose-Xylitol Mixture fructosemia fructoside fructosuria fructosuria fructosyl Fructosyl-Amino Acid Oxidase Fructuary Fructuation Fructuosus Fructuosus of Tarragona Fructuosus of Tarragona, Saint fructuous Fructure fructus Fructus industriales Fructus industriales Fructus industriales Fructus naturales Fructus pendentes pars fundi videntur Fructus perceptos villae non esse constat FRUD

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