freeze substitution

freeze substitution

a physiochemical process in which water frozen within cells is replaced by organic solvents at subzero temperatures; widely used as an aid for ultrastructural and immunocytochemical analysis of cells by electron microscopy.
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Contract notice: Supply, Delivery and installation of high pressure freezing equipment and freeze substitution processor.
Bal-Tec AG's products include high-pressure and jet freezers, freeze-fracture systems, cryo transfer systems, freeze substitution systems and ion milling systems.
Ultrstructure of hypertrophic cartilage: histochemical procedures compared with high pressure freezing and freeze substitution.
Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding.
The ultrastructure of the connective tissue matrix of skin and cartilage after high pressure freezing and freeze substitution.
The freezer is available with a metal mirror kit for impact freezing samples, adaptors for cryotransfer units, and freeze substitution modules.
Freezing stress response in woody tissues observed using low temperature scanning electron microscopy and freeze substitution techniques.
Leica also introduced a number of specimen preparation products, including a high pressure freezer, automatic freeze substitution systems anda new ultramicrotome.