freeze fracture


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freeze frac·ture

a procedure for preparing cells or other biologic samples for electron microscopy in which the sample is frozen quickly and then broken with a sharp blow.
Synonym(s): cryofracture

freeze frac·ture

(frēz frak'shŭr)
A procedure for preparing cells or other biologic samples for electron microscopy during which the sample is frozen quickly and then broken with a sharp blow.
Synonym(s): cryofracture.
References in periodicals archive ?
The finding on freeze fracture analysis that the cultured cells possessed tight junctional sealing strands further suggested a level of differentiation similar to the apical intermediate layer of the bladder urothelium.
Additional gland tissue, fixed as described above but in aldehydes only, was cryoprotected in graded concentrations of glycerols to a final concentration of 30% glycerol for freeze fracture.