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free thyroxine index |
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free thyroxine index, the amount of unbound, physiologically active thyroxine (T4) in serum. This amount is determined by direct assay or, more frequently, calculated on the basis of an in vitro uptake test. In this test the uptake (by resin or charcoal) of labeled triiodothyronine (T3) is measured; because T3 is less strongly bound by serum, it is used instead of T4. The free T4 index is then obtained by multiplying the T3 uptake by the total concentration of T4 in serum. free thyroxine index FT4I, T7 assay, T12 assay Endocrinology A lab value for T3 uptake combined with total T4; FTI is a clinical parameter measured by RIA, used to evaluate thyroid function, calculated by
T4 x %T3RU–resin uptake; the FTI is ↑ in hyperthyroidism and factitious hyperthyroidism and ↓ in hypothyroidism; it is falsely ↑ in heparin therapy and falsely ↓ in phenytoin and valproic acid therapy,
and in the euthyroid sick syndrome. See Thyroxine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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What are the advantages and disadvantages of replacing a calculated a free thyroxine index (FTI) with a directly determined free T4. 4]) and free thyroxine index (FTI) in women and with significantly lower levels of [T. The serum free thyroxine index increased significantly, but there was no change in serum |
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