framework region

framework region

in immunology, a conserved sequence of amino acids on either side of the hypervariable regions in the variable domains of an immunoglobulin chain.

frame·work re·gion

(frām'wŏrk rē'jŭn)
immunology A conserved sequence of amino acids on either side of the hypervariable regions in the variable domains of an immunoglobulin chain.
References in periodicals archive ?
Le service structures will be in charge of a mission comprising three phases (3) Phase 1: Analysis of possible legal framework Region Intervention Phase 2: needs Analysis Ile-de-FrancePhase 3: Production of a pre-operational study of a support device with its legal framework and a study financier.
Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

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