fosfomycin


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antibacterial

 [an″te-, an″ti-bak-tēr´e-al]
1. destroying or suppressing the growth or reproduction of bacteria.
2. an agent having such properties.

fosfomycin

/fos·fo·my·cin/ (fos-fo-mi´sin) an antibacterial agent active against a wide range of gram-positive and gram-negative bacteria, used in the treatment of urinary tract infection; administered orally as the tromethamine salt.

fosfomycin

a urinary antiinfective.
indications It is used to treat infections of the urinary tract caused by Enterococcus faecalis and Escherichia coli.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects include vaginitis, dysuria, hematuria, menstrual disorder, fever, insomnia, somnolence, migraine, asthenia, nervousness, constipation, dry mouth, flatulence, increased SGPT, dyspepsia, and pruritus. Common side effects are headache, dizziness, nausea, vomiting, anorexia, diarrhea, and rash.

fosfomycin

a phosphonic acid compound with antibacterial activity.
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References in periodicals archive ?
Only 1 CRE- positive isolate was tested against fosfomycin.
Fosfomycin and mecillinam susceptibilities were retrospectively performed on non duplicate patient isolates.
coli strains to other commonly used agents, such as ciprofloxacin and trimethoprim/sulfamethoxazole, fosfomycin has become one of the first-line agents recommended for treatment of uncomplicated urinary tract infection.
Fosfomycin is successfully used for the treatment of UTIs in many European countries but is currently not funded in New Zealand.
Fosfomycin is active against many resistant organisms such as vancomycin-resistant Enterococcus, MRSA, and beta-lactamase-producing agents.
The low rates of resistance to nitroturantoin and fosfomycin are felt to be secondary to their minimal effects on fecal flora.
The antimicrobial drugs resistance was investigated using different antibiotics namely amoxicillin/clavulanic acid, erythromycin, enrofloxacin Baytril, fosfomycin, neomycin, Penicillin G, streptomycin, sulphamethoxazole/ trimethoprim, and tetracycline.
All strains were susceptible to ampicillin, cephalothin, cefotaxime, enrofloxacin, nalidixic acid, gentamicin, streptomycin, chloramphenicol, fosfomycin, tetracycline, nitrofurantoin, and trimethoprimsulfamethoxazole.
Nitrofurantoin or fosfomycin (urinary tract infection only)
Susceptibility and resistance data suggests more prominent future roles for nitrofurantoin and fosfomycin
Contract awarded for fosfomycin trometamol, powder for oral solution 3 g, single-dose