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fosfomycin |
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fosfomycin /fos·fo·my·cin/ (fos-fo-mi´sin) an antibacterial agent active against a wide range of gram-positive and gram-negative bacteria, used in the treatment of urinary tract infection; administered orally as the tromethamine salt. fosfomycin a phosphonic acid compound with antibacterial activity. |
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It was sensitive to ampicillin, cefotaxime, cefuroxime, ceftriaxone, imipenem, ciprofloxacin, gentamicin, trimethoprim-sulfamethoxazole, and fosfomycin but resistant to clarithromycin (MIC 96 mg/L). Combining fosfomycin with an aminoglycoside has been repeatedly shown to protect from ototoxicity, although the reason it does so is unclear. The strain was susceptible to fluoroquinolones and fosfomycin. |
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