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foscarnet

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foscarnet /fos·car·net/ (fos-kahr´net) a virostatic agent used as the sodium salt in the treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients.
foscarnet [fos-kahr´net]
an agent that inhibits replication of viruses, used as the sodium salt in treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients.

foscarnet
a pyrophosphate analog used as an antiviral agent against herpesviruses.

foscarnet
AIDS An antiviral for treating CMV colitis, hepatitis, pneumonia, retinitis; acyclovir resistant HSV, nonresponders to gancyclovir; foscarnet inhibits other herpes viruses and HIV; being studied for treatment of KS Adverse effects Renal damage, meatus rash, which may disappear even if foscarnet is discontinued. See AIDS. Cf ddC, ddI, Zidovudine.


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Mutations in the UL54 DNA polymerase gene have been associated with resistance to the medications ganciclovir, foscarnet, and cidofovir.
Anti-CMV therapy exists in various forms (intravenous, oral and intravitreal) and includes ganciclovir, valganciclovir, foscarnet and cidofovir.
 
 
 
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