Calycosin and Formononetin
were potential for asthma treatment by inhibiting the expression of the TGF-[beta]1/Smad signaling pathway (Qu et al.
In a recent double-blind, randomized, placebo-controlled trial, 177 women aged 49-65 years received a red clover-derived isoflavone supplement that provided a daily dose of 26 mg biochanin A, 16 mg formononetin
, 1 mg genistein and 0.
In addition to containing the two isoflavones found in soy known to have significant estrogenic properties, genistein and daidzein, Promensil contains two additional isoflavones, formononetin
and biochanin, which have been shown to bind to estrogen receptors to produce estrogen-like effects.
Professor Alan Husband, Research Director of Novogen, said, "This finding raises the possibility of using formononetin
as a safe alternative for the maintenance of bone density and the treatment of osteoporosis.
Before surgery 20 men consumed 160 mg/day of red clover-derived dietary isoflavones, which contained a mixture of genistein, daidzein, formononetin
and biochanin A.
The isoflavone formononetin
prevents bone loss by reversing estrogen deficiency-induced detrimental bone biomechanical features (Kaczmarczyk-Sedlak et al.
Promensil contains 40 mg of red clover isoflavones, including genistein, biochanin, daidzein and formononetin
atractylodin Cnidii Rhizoma Ferulic acid, ligustilide Uncariae Uncis Geissoschizine methyl erther, hirsuteine, hirsutine cum Ramulus Angelicae Radix Xanthotoxin, ligustilide Bupleuri Radix Saikosaponin b1, saikosaponin b2 Glycyrrhizae Formononetin
-7-O-glucoside Radix Liquiritigenin, liquiritin, liquiritin apioside, glycyrrhizin, glycyroside, isoliquiritin apioside.
Trinovin delivers a standardized ratio of four isoflavones, including biochanin, formononetin
, daidzein and genistein," says Katz.
Constituent of Compounds TJ-54 Atractylodis 4E,6E,12E-Tetradecatriene-8,10-diyne-1,3,14-triol, lanceae Rhizoma 12-isovaleroyl-2E,8E,10E-triene-4,6-diyne-1,14- diol 14-isovaleroyl-2E,8E,10E-triene-4,6-diyne- 1,12-diol, atractylodin Cnidii Rhizoma Ferulic acid, ligustilide Uncariae Uncis Geissoschizine methyl erther, hirsuteine, hirsutine cum Ramulus Angelicae Radix Xanthotoxin, ligustilide Bupleuri Radix Saikosaponin b1, saikosaponin b2 Glycyrrhizae Formononetin
-7-O-glucoside Radix Liquiritigenin, liquiritin, liquiritin apioside, glycyrrhizin, glycyroside, isoliquiritin apioside, isoliquiritin, isoliquiritigenin, glycycoumarin Table 2 Effect of yokukansan on the emotional abnormality of mice induced by exposure to a single restraint stress.
accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERR and p38 MAPK pathways.
Liquiritin Liquiritin apioside Liquiritigenin Isoliquiritin Isoliquiritin apioside Isoliquiritigenin Rosmarinic acid Clycycoumarin Glycyrrhizin Formononetin Formononetin
7-0-glucoside Narirutin Hesperidin AN P-2 AN P-4 6-Gingeroi 6-Shogaol