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formalin |
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formalin /for·ma·lin/ (for´mah-lin) formaldehyde solution.
formalin [fôr′məlin] a clear solution of formaldehyde in water. A 37% solution is used for fixing and preserving biologic specimens for pathologic and histologic examination. formalin (for´m n a clear aqueous solution of formaldehyde. A 37% solution is used to fix and preserve tissues for histologic and pathologic study. formalin a 37% solution of formaldehyde used as a fixative and, diluted to 10%, as a treatment and prevention for ovine footrot. Also used for the treatment of fungal diseases of fish but may be toxic if contaminated with paraformaldehyde. formalin ether sedimentation of feces a method of flotation of Giardia cysts. formalin treated grain fed to cows to produce dairy foods with a high concentration of polyunsaturated fats. May cause rumenitis and diarrhea if improperly prepared. formalin Pathology A 37% solution of formaldehyde gas in water, that reacts with the amine groups of proteins and DNA, which acts to disinfect, and when buffered, to denature–'fix' tissues for histologic examination. Cf
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It was fixed in 10% buffered formalin and embedded in paraffin. Introduced by Dubuisson and Dennis in 1977, the formalin test is used widely to evaluate analgesic drugs, and it is well known as an animal model of tonic inflammatory pain. While we wait for more of these products to hit the market, Guard is still a proponent of using formalin in footbaths due to efficacy and low cost. |
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