FOXL2

(redirected from forkhead box protein L2)

FOXL2

A gene on chromosome 3q23 that encodes a member of the forkhead family of transcription factors, which is thought to play a role in ovarian development and function.

Molecular pathology
FOXL2 mutations cause blepharophimosis syndrome and premature ovarian failure 3.
References in periodicals archive ?
The article also delineates the application of many recently introduced IHC markers, such as (1) loss of expression of PAX2 in invasive and in situ endocervical adenocarcinomas, (2) strong and diffuse nuclear expression of cyclin D1 in high-grade endometrial stromal sarcomas, (3) expression of hepatocyte nuclear factor 1[beta] (HNF-1[beta]) and napsin A in clear cell carcinomas of the uterus and ovary, (4) forkhead box protein L2 (FOXL2) and steroidogenic factor 1 (SF1) as sensitive and specific markers for sex cord and stromal tumors, and (5) loss of expression of p57 in complete hydatidiform moles.

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