foreign body reaction

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Related to foreign body reaction: foreign body granuloma


1. not normal or usual to a place.
2. in immunology, pertaining to substances not recognized as “self” and capable of inducing an immune response.
foreign body reaction a granulomatous inflammatory response evoked by the presence of a foreign body in the tissues; a characteristic feature of this is the formation of foreign body giant cells (see giant cell).

for·eign bod·y re·ac·tion

(fōrin bodē rē-akshŭn)
Protective response by the immune system to a foreign body; includes chronic inflammation and granulomatous formations around the intrusive object.

foreign body reaction

A localized inflammatory response elicited by any material (e.g., a splinter or a suture) that would not normally be found within the body.
References in periodicals archive ?
The use of mesh in this patient, with the concomitant inflammatory foreign body reaction, may have lead to the development of an umbilical endometrioma.
In the reconstruction of hernias and other soft tissue deficiencies, reducing the risk of pain-related complications means minimizing chronic foreign body reaction - the adverse impact on the body's own natural healing process.
Our extensive pre-clinical testing has shown that mitral valve repairs completed with the low profile U-CLIP(TM) withstand supraphysiologic pressures and heal perfectly with no foreign body reaction.
The result is a foreign body reaction with inflammatory cells, granulation tissue, and secondary infection (1).
Although rare, some of the known risks of surgical procedures for the treatment of pelvic organ prolapse include the following: adhesion formation, mild to severe bleeding (hematoma, perforation of vessels), constipation, complete failure of the procedure resulting in recurrent pelvic organ prolapse, dyspareunia, de novo prolapse of an untreated compartment, fecal incontinence, foreign body reaction, infection, graft erosion, graft extrusion, graft migration, nerve damage, obstruction of the ureter, pain, perforation of: bladder, bowel, ureter, urethra, and other pelvic structures, urinary tract infection, vaginal contracture, voiding dysfunction, and wound dehiscence.
Intraperitoneal administration of a product with particulate matter may cause local inflammation with foreign body reaction or result in adhesion formation.
The cysts are formed when keratin is found within or below the skin and the keratin causes a foreign body reaction.