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food and drug interactions

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food and drug interactions,
adverse health effects of certain combinations of foods and medications. Examples include reduced activity of drug-metabolizing enzymes (e.g., grapefruit juice is an inhibitor), and interference with the absorption of the drug (e.g., calcium inhibits tetracycline absorption from the GI tract).


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Warfarin has multiple food and drug interactions, as well.
Limitations of VKAs include a slow onset of action, a narrow therapeutic window necessitating regular coagulation monitoring and dose adjustment, and multiple food and drug interactions.
 
 
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