food and drug interactions


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food and drug interactions

adverse health effects of certain combinations of foods and medications. Examples include reduced activity of drug-metabolizing enzymes (e.g., grapefruit juice is an inhibitor), and interference with the absorption of the drug (e.g., calcium inhibits tetracycline absorption from the GI tract).

food and drug interactions

The effect of nutrients on the absorption, distribution, metabolism or excretion of medications. For example, alkaloids in potatoes may influence the effects of anesthetics; excess intake of vegetables rich in vitamin K may interfere with the action of anticoagulants; prolonged use of antacids may cause phosphate depletion; consumption of grapefruits or grapefruit juice may influence the half-life of some antiretroviral drugs.
See also: interaction
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