follistatin


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fol·li·stat·in

(fol'i-stat'in), [MIM*136470]
A peptide synthesized by granulosa cells in response to FSH that suppresses FSH activity, probably by binding activins.
[follicle + -stat + -in]

fol·li·stat·in

(fol'i-stat'in)
A peptide synthesized by granulosa cells in response to FSH, which suppresses FSH activity, probably by binding activins.
[follicle + -stat + -in]

follistatin

(fŏl″ĭs-tă′tĭn) [ folli(cle) + ″]
A protein that regulates the actions of activins in the body. It antagonizes the effects of many members of the transforming growth factor family of cytokines. One function of follistatin is to decrease the secretion of FSH.

follistatin

a gonadal peptide hormone isolated from the ovarian follicular fluid. Suppresses FSH secretion.
References in periodicals archive ?
Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines.
Drugs profile mention in this report includes alpha-1 proteinase inhibitor (human), Elafin, FX-06, R-503, R-801, Recombinant Human Follistatin, RNAi Oligonucleotide for Lung Diseases.
Drug profiles provided in the report cover alpha-1 proteinase inhibitor (human) second generation, ALT-07, ALT-09, ARD-3150, BAY-858501, CG-1011, ciprofloxacin, dapsone, erdosteine, GSK-2793660, Leukotriene B4, levofloxacin, molgramostim, Recombinant Human Follistatin and vancomycin hydrochloride.
The BMP antagonists follistatin and gremlin in normal and early osteoarthritic cartilage: an immunohistochemical study.
Plasma follistatin is elevated in patients with type 2 diabetes: relationship to hyperglycemia, hyperinsulinemia, and systemic low-grade inflammation.
Differential downregulation of follistatin leads to asymmetric distribution of enamel, which is responsible for individual tooth morphology [Caton and Tucker, 2009].
Under this deal, DSM will develop and produce Paranta Biosciences lead recombinant human protein - follistatin.
FSTL1 is a secreted protein sharing a characteristic structural module, the follistatin domain, with follistatin, FSTL3, and members of the SPARC (secreted protein acidic and rich in cysteine) matrix protein family (32).
2007), follistatin (Lee, 2007; Lee and McPherron, 2001), histone deacetylase inhibitor (Iezzi et al.
Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin.
Inhibin, activin, and follistatin in human fetal pituitary and gonadal physiology.