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follicular cell |
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Follicular cell hypertrophy and pale-staining colloid were present in thyroid glands from PB-treated rats, and more severe hypertrophy/colloid changes along with diffuse hyperplasia were present in thyroid glands from PTU-treated rats. The follicular cells typically exhibit severe cytologic atypia, including bizarre and markedly enlarged, hyperchromatic nuclei (figure, B). In the Phase II clinical trial in NHL, 27 of a planned 40 patients with small lymphocytic (n=9), mantle cell (n=5), marginal zone (n=2) and follicular cell (n=11) lymphoma have been enrolled. |
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