follicular carcinoma

fol·lic·u·lar car·ci·no·ma

carcinoma of the thyroid composed of well-differentiated or poorly differentiated epithelial follicles without papillary formation, which is difficult to distinguish from adenoma; the criteria include blood vessel invasion and the finding of metastases of follicular thyroid tissue in other structures such as cervical lymph nodes and bone; follicular carcinoma may take up radioactive iodine.

fol·lic·u·lar car·ci·no·ma

(fŏ-lik'yū-lăr kahr'si-nō'mă)
Carcinoma of the thyroid composed of well or poorly differentiated epithelial follicles without papillary formation, which is difficult to distinguish from adenoma; the criteria include blood vessel invasion and the finding of metastases of follicular thyroid tissue in other structures such as cervical lymph nodes and bone; follicular carcinoma may take up radioactive iodine.
References in periodicals archive ?
Thyroid gland follicular carcinoma is a malignant epithelial neoplasm of follicular cell differentiation that exhibits capsular and/or lymphovascular invasion while lacking the nuclear features of thyroid papillary carcinoma.
The test consists of a panel comprised of eight genes associated with papillary and follicular carcinoma, the two most common forms of thyroid malignancies.
A referral for operative exploration is recommended in such cases; usually, a hemi-thyroidectomy or lobectomy is performed, followed by histologic examination for capsular and vascular invasion to distinguish between follicular adenoma and follicular carcinoma (13), (15).
A rare morphologic subtype of RCC, thyroidlike follicular carcinoma of the kidney, is characterized by a follicular, partially cystic, architectural pattern mimicking metastatic thyroid carcinoma.
This case describes a patient with thyroid cancer who suffered complete superior vena cava obstruction as a result of follicular carcinoma metastasis into the SVC, creating a massive venous thrombus.
RAS point mutations and PAX8-PPAR[gamma] rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.
Also, the absence of well differentiated regions, such as papillary or follicular carcinoma in angiosarcomas, in contrast to anaplastic carcinomas, is another characteristic that is used for differentiation.
Follicular carcinoma was diagnosed in 15 patients, and the balance had papillary carcinoma of the thyroid.
14 cases were diagnosed cytologically as benign follicular cells, histopathologically were diagnosed as follows: 2 cases microfollicular adenoma, 2 cases as lymphocytic thyroiditis 8 cases as diffuse hyperplaslic thyroid tissue and 2 cases as follicular carcinoma two cases were diagnosed cytologically as undifferentiated malignant cells histopathologically was diagnosed as malignant lymphoma.
Papillary carcinoma was the pathology in 14 of 17 cases; follicular carcinoma was identified in 2 cases, and medullary carcinoma in 1.
Intended for both pathologists and endocrinologists, this reference collects the different approaches required to manage papillary carcinoma, follicular carcinoma, medullary thyroid carcinoma, thyroid lymphomas, and anaplastic cancers.